Zimmer's had success vs. Foles in the past, but I don't even think it matters to a significant degree, because game managers create by what's around them not successful creators that force the issue/offense through their own talents.
Eagles, obviously different roster than the one Foles was with as a Ram. With Ajayi, Blount, Jeffrey, Ertz, Foles who is a more-than-quasi-game-manager QB will defer to his weapons as he's always done outside of that weird 2-INT year where he was thought to be potentially great.
Zimmer needs to attack him how he's been beaten this year, since he'll look different to Zimmer in how he's "running" the offense compared to past matchups with like Tavon Austin, etc.
Alshon Jeffrey turned down more money from Minnesota a year ago to sign with the Wentz/Eagles tandem and now he'll have to make plays for Foles or watch Minnesota head to the Super Bowl. Alternative universe-wise it's kind of a weird subplot for him, personally.