- Feb 23, 2010
- 23,399
- 26,477
I've noticed some discrepancy in whether someone who was previously infected should wait or take the vaccine when offered to them. CDC has said there is no reason to wait, however Fauci stated they should wait 90 days to avoid interaction between antibodies and the vaccine. I'm not smart enough to understand fully, but to me it seems like the same antibodies present after natural infection would also exist after your initial vaccine dose. Since you only have to wait 21-28 days before receiving your second dose, what's the reason to wait 90 days after infection? It would make more sense that you'd wait 30 days, at most.
the only reason I can think of off the top of my head is that the immune cells from the initial infection response might instead move over to the inactivated spike protein made by the vaccine? I assume the timing they gave depends on the lifespan of the cells involved but I'm not sure.