- Oct 28, 2013
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Hide Ya Wives, Hide Ya Kids: Worldwide Coronavirus Pandemic!
solewoman
Staff member
- Jul 27, 2006
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- Jun 25, 2013
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I'm in mont cnty. It's a lil crazy I'll admit.
solewoman
Staff member
- Jul 27, 2006
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I’m in PG. he’s definitely playing the wrong hand.
- Apr 15, 2007
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That article title is misleading though. Hogan is saying the counties can't make a blanket order to shut down schools. The shut downs should be decided by the individual schools themselves
- Jul 27, 2013
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| Kansas State University | News and Communications Services
www.k-state.edu
MANHATTAN — Yunjeong Kim and Kyeong-Ok "KC" Chang, virologists in the College of Veterinary Medicine at Kansas State University, have published a study showing a possible therapeutic treatment for COVID-19.
Pathogenic coronaviruses are a major threat to global public health, as shown by severe acute respiratory syndrome coronavirus, or SARS-CoV; Middle East respiratory syndrome coronavirus, known as MERS-CoV; and the newly emerged SARS-CoV-2, the virus that causes COVID-19 infection.
The study, "3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice," appears in the Aug. 3 issue of the prestigious medical journal Science Translational Medicine. It reveals how small molecule protease inhibitors show potency against human coronaviruses. These coronavirus 3C-like proteases, known as 3CLpro, are strong therapeutic targets because they play vital roles in coronavirus replication.
"Vaccine developments and treatments are the biggest targets in COVID-19 research, and treatment is really key," said Chang, professor of diagnostic medicine and pathobiology. "This paper describes protease inhibitors targeting coronavirus 3CLpro, which is a well-known therapeutic target."
The study demonstrates that this series of optimized coronavirus 3CLpro inhibitors blocked replication of the human coronaviruses MERS-CoV and SARS-CoV-2 in cultured cells and in a mouse model for MERS. These findings suggest that this series of compounds should be investigated further as a potential therapeutic for human coronavirus infection.
Chang and Kim have been using National Institutes of Health grants to develop antiviral drugs to treat MERS and human norovirus infections. Their work extends to other human viruses such as rhinoviruses and SARS-CoV-2.
"The work that this group of collaborators has been doing on antivirals and inhibitors for SARS and MERS at K-State for a number of years has been vital to their ability to quickly pivot to emphasize research on SARS-CoV-2 virus and therapeutics," said Peter K. Dorhout, vice president for research at K-State.
Co-collaborators on the research include teams lead by Bill Groutas at Wichita State University, Stanley Perlman at the University of Iowa and Scott Lovell at the University of Kansas.
"Drs. Groutas, Perlman and Lovell brought decades of experience to our research team," Chang said. "We would not have been able to come this far without important collaborations with our colleagues at other institutions."
“Getting things published right now is very important for the scientific community," Kim said. "I think we are adding valuable information to the antiviral field."
The new compounds in the publication are exclusively licensed and being developed by Cocrystal Pharma for COVID-19. K-State Innovations Partners handles commercial technology licensing for the university.
solewoman
Staff member
- Jul 27, 2006
- 19,653
- 21,637
That makes no sense because it will make it harder for governments to make decisions about work.
- Jul 27, 2013
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$COCP
- Feb 24, 2009
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Not disagreeing with you on some of the points you made but I’m just saying you can’t boost your immune system.
There is no way to measure immune system performance to determine if it is low or high. At least that I know of.
Of course there are things you can do to prevent yourself from getting sick more often.
- Aug 5, 2007
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my state really looking stupid nowadays. last week or so we had our first triple digit day and now we doubled that 
- Mar 30, 2007
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- Jul 27, 2013
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my state really looking stupid nowadays. last week or so we had our first triple digit day and now we doubled that
Hanalei it is!!!
- Feb 16, 2011
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I disagree man, as far as locals go at least on oahu...everyone been very compliantmy state really looking stupid nowadays. last week or so we had our first triple digit day and now we doubled that
The narrative is that “we are letting up and becoming complacent” becoming too relaxed and letting down our guard.....
I also disgree, if you look at the number of daily visitors coming to oahu and compare them with the recent spikes you will see the correlation...it couldn’t be clearer.
state officials don’t want to put the blame on tourists/tourism because you know why.....
I get it but don’t be out here pointing fingers at locals like we ain’t doing our part and are the cause for the spike....
Im seeing right through it
- Mar 27, 2004
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I don't disagree.No way does Cuomo get a pass for his response. Outrageous he has the cajones to pat himself on the back. Total BS.
Not letting any politician get away with such narcissism. How stupid and how short does he imagine the Public’s memory is? What an arrogant pos. Even reasonable non conservatives and non Republicans won’t believe the Lie.
Look at those Numbers.
Andrew Cuomo's Coronavirus Response Has Been a Failure
If you're wondering how New York Gov. Andrew Cuomo sees his state's response to COVID-19, check out the pandemic poster he…reason.com
Jake Tapper tears into Cuomo for touting New York's COVID response: There are 'more than 32,000 dead New Yorkers'
CNN has largely refrained from offering critical coverage of New York Gov. Andrew Cuomo's handling of the coronavirus pandemic, but anchor Jake Tapper tore into him on Tuesday after the Democrat appeared on late-night TV and unveiled merchandise touting his state's response to the virus.www.foxnews.com
Cuomo official grilled on virus nursing home deaths, secrecy
Lawmakers are holding hearings geared at understanding why and how the pandemic took root in New York nursing homes.www.syracuse.com
Cuomo admits NY made ‘a lot of mistakes’ in coronavirus fight
Gov. Andrew Cuomo admitted Monday that New York made “a lot of mistakes” in its battle against coronavirus which has so far claimed 25,056, according to state data. “It is hard. We made a lot of mi…nypost.com
I should've phrased it more as a "how stupid is the rest of the country's leaders" as opposed to "how great was Cuomo's handling of the virus."
The credit I give Cuomo is for holding daily briefings and for imparting to the public how serious things were. But he and the state also did terribly on a number of other things and he should leave it to others to criticize how badly other states have done.
- Oct 18, 2011
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Cuomo and Di Blasio were too busy trying to one up each other instead of addressing shutting down in a timely fashion.
- Jan 20, 2002
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Georgia teenager loses both parents to COVID-19 within a week
A Georgia teenager who lost both his parents to COVID-19 within a week is urging people to take precautions during the pandemic. Justin Hunter told Atlanta ABC affiliate WSB that he and his parents had all tested positive for the coronavirus last month. "Their temperature skyrocketed, they had...
- Sep 24, 2015
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Not all people can build up their immune system buddy. I take immunosuppressant medication to turn off my immune system. It's done so my immune system won't attack the transplanted liver inside me. I dread the coming winter months as it's gonna be bad around here. I for the most part stay at home, with little interaction in stores. Plus I only drink water and the occasional unsweetened tea with lemon, eat fish, turkey & chicken, and get 7-8 hours of sleep a night, and do at least 10,000 steps a day walking around my neighborhood while out on disability for Crohn's (being out of work has lowered my stress a bunch too). But all this still won't help me as I don't have an immune system to build up.
But at least I'm doing safe practices. All groceries are curbside, medications are picked up via drive-thru. If I do need to actually go into a store, it's don't 15 minutes before they close (Aldi) as there is basically no one inside shopping other than my wife & I. Even Costco, which I dreaded going to, opens up an hour early for high risk and elderly. Only place I could get paper towels. I was in, and out in 10 minutes. Not everyone can pump up their systems. I only wish as I would be less afraid of catching this (as it would do serious damage to me if I got it).
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- Dec 23, 2003
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Keep you and your family safe bro as best you canmy state really looking stupid nowadays. last week or so we had our first triple digit day and now we doubled that
- Aug 5, 2007
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dude, have you been by the beach lately? do you see the IG stories of big family gatherings? the only positive i see are the stores requiring masks but even then, tons wearing them with the nose exposed. i work closely with the DOH and the community spread has been the driving factor in the number of case increases. lots of idiots not adhering to the visitor quarantine but that’s not it man.
case in point:
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- Feb 24, 2016
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K-12 schools and colleges can reopen, but safety should come first, Fauci says
www.cnn.com
K-12 schools and colleges can reopen, but safety should come first, Fauci says
Dr. Anthony Fauci said Monday safety and testing need to be a priority when determining whether to re-open schools and colleges.
www.cnn.com
T0INE
formerly toine2983
- Dec 21, 2005
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Welp.
Prime Minister just announced that the entire country is on lockdown again for at least the next few weeks.
Can only go out for essentials (grocery, pharmacy, gas etc.) 3 days a week.
Since the last time I checked in here the number of cases over here jumped to damn near 700.
Prime Minister just announced that the entire country is on lockdown again for at least the next few weeks.
Can only go out for essentials (grocery, pharmacy, gas etc.) 3 days a week.
Since the last time I checked in here the number of cases over here jumped to damn near 700.
- Mar 30, 2007
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Welp.
Prime Minister just announced that the entire country is on lockdown again for at least the next few weeks.
Can only go out for essentials (grocery, pharmacy, gas etc.) 3 days a week.
Since the last time I checked in here the number of cases over here jumped to damn near 700.
never should have opened for travel in or out, until tests were readily available and you’re able to restrict and track
butvi don’t expect much from Minnis or this crew.. Minnis failed up, didn’t really have to do shh as a MP or minister before falling back into leadership of the FNM then people being pissed at Christie and certain folks just like ‘07
T0INE
formerly toine2983
- Dec 21, 2005
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Seeing all them Bahamians crowded up at the airport to go to Florida.
Should've turn them around and sent there *** home.
They gonna be the main ones complaining about the lockdown when they were the primary cause of it.
