Only if I play for like 3 days straight, fullcourt for several games. And the knee pain only requires a day or two of rest. I've got knee tendonitis, so if I play on a phylon shoe for 2-3 days straight sometimes the pain takes a full week of rest to go away. The CE and the Rose 6 have been a damn miracle on my knees, actually. I know they don't feel as comfy as the boost runners, but the impact protection is no joke.
All you high school young bucks out there, when your knees eventually start getting funny, go with a good boost shoe and it'll feel like you shaved off years.